Surface modification of zirconia substrate by silicon-substituted hydroxyapatite coating for enhanced bioactivity

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bioactivity enhancement of hydroxyapatite by silicon substitution

objective: silicon is an effective element in bone biomineralization; hence si-substituted hydroxyapatite can be a relevant bioceramic as bone materials substitution. materials and methods: stoichiometric hydroxyapatite (ha) and si-substituted hydroxyapatite (si-ha) with different contents of si substitution were synthesized successfully by a hydrothermal method using ca(no3)2, (nh4)3po4 or (n...

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Hydroxyapatite coating on porous zirconia

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Surface modification for titanium implants by hydroxyapatite nanocomposite

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Facilitated receptor-recognition and enhanced bioactivity of bone morphogenetic protein-2 on magnesium-substituted hydroxyapatite surface

Biomaterial surface functionalized with bone morphogenetic protein-2 (BMP-2) is a promising approach to fabricating successful orthopedic implants/scaffolds. However, the bioactivity of BMP-2 on material surfaces is still far from satisfactory and the mechanism of related protein-surface interaction remains elusive. Based on the most widely used bone-implants/scaffolds material, hydroxyapatite ...

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Silicon-substituted hydroxyapatite nanocomposite: Synthesis, characterization and in vitro bioactivity study in Human Serum Albumin

Nano hydroxyapatite and Silicon-substituted hydroxyapatite nanocomposites with various amount of Si contents (0, 2, 4 and 6 mole % as named as HS0, HS2, HS4 and HS6) were prepared via in situ hybridization method and were analyzed by XRD, FTIR, SEM and AFM techniques. Size distribution of the products demonstrated that hydroxyapatite particles size was between 2 and 53.5 nm with further mean si...

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ژورنال

عنوان ژورنال: Journal of the Ceramic Society of Japan

سال: 2018

ISSN: 1348-6535,1882-0743

DOI: 10.2109/jcersj2.18108